1zs0
From Proteopedia
Crystal structure of the complex between MMP-8 and a phosphonate inhibitor (S-enantiomer)
Template:ABSTRACT PUBMED 16451058
About this Structure
1ZS0 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Structural insight into the stereoselective inhibition of MMP-8 by enantiomeric sulfonamide phosphonates., Pochetti G, Gavuzzo E, Campestre C, Agamennone M, Tortorella P, Consalvi V, Gallina C, Hiller O, Tschesche H, Tucker PA, Mazza F, J Med Chem. 2006 Feb 9;49(3):923-31. PMID:16451058
X-ray structure of human stromelysin catalytic domain complexed with nonpeptide inhibitors: implications for inhibitor selectivity., Pavlovsky AG, Williams MG, Ye QZ, Ortwine DF, Purchase CF 2nd, White AD, Dhanaraj V, Roth BD, Johnson LL, Hupe D, Humblet C, Blundell TL, Protein Sci. 1999 Jul;8(7):1455-62. PMID:10422833
Two crystal structures of human neutrophil collagenase, one complexed with a primed- and the other with an unprimed-side inhibitor: implications for drug design., Gavuzzo E, Pochetti G, Mazza F, Gallina C, Gorini B, D'Alessio S, Pieper M, Tschesche H, Tucker PA, J Med Chem. 2000 Sep 7;43(18):3377-85. PMID:10978185
X-ray structures of human neutrophil collagenase complexed with peptide hydroxamate and peptide thiol inhibitors. Implications for substrate binding and rational drug design., Grams F, Reinemer P, Powers JC, Kleine T, Pieper M, Tschesche H, Huber R, Bode W, Eur J Biochem. 1995 Mar 15;228(3):830-41. PMID:7737183
Page seeded by OCA on Mon Jul 28 11:31:53 2008
Categories: Homo sapiens | Neutrophil collagenase | Single protein | Agamennone, M. | Campestre, C. | Consalvi, V. | Gallina, C. | Gavuzzo, E. | Hiller, O. | Mazza, F. | Pochetti, G. | Tortorella, P. | Tschesche, H. | Tucker, P A. | Phosphonic inhibitor | Stereoselective inhibition | Sulphonamide junction