2b4s

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Image:2b4s.png

Template:STRUCTURE 2b4s

Contents

Crystal structure of a complex between PTP1B and the insulin receptor tyrosine kinase

Template:ABSTRACT PUBMED 16271887

Disease

Known disease associated with this structure: Diabetes mellitus, insulin-resistant, with acanthosis nigricans OMIM:[147670], Hyperinsulinemic hypoglycemia, familial, 5 OMIM:[147670], Leprechaunism OMIM:[147670], Rabson-Mendenhall syndrome OMIM:[147670]

About this Structure

2B4S is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Crystal structure of a complex between protein tyrosine phosphatase 1B and the insulin receptor tyrosine kinase., Li S, Depetris RS, Barford D, Chernoff J, Hubbard SR, Structure. 2005 Nov;13(11):1643-51. PMID:16271887

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