2f3e

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Template:STRUCTURE 2f3e

Crystal Structure of the Bace complex with AXQ093, a macrocyclic inhibitor

Template:ABSTRACT PUBMED 16854060

About this Structure

2F3E is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Structure-based design and synthesis of macroheterocyclic peptidomimetic inhibitors of the aspartic protease beta-site amyloid precursor protein cleaving enzyme (BACE)., Hanessian S, Yang G, Rondeau JM, Neumann U, Betschart C, Tintelnot-Blomley M, J Med Chem. 2006 Jul 27;49(15):4544-67. PMID:16854060

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