2f7z
From Proteopedia
Protein Kinase A bound to (R)-1-(1H-Indol-3-ylmethyl)-2-(2-pyridin-4-yl-[1,7]naphtyridin-5-yloxy)-ehylamine
Template:ABSTRACT PUBMED 16413780
About this Structure
2F7Z is a Single protein structure of sequence from Bos taurus. Full crystallographic information is available from OCA.
Reference
Synthesis and structure-activity relationship of 3,4'-bispyridinylethylenes: discovery of a potent 3-isoquinolinylpyridine inhibitor of protein kinase B (PKB/Akt) for the treatment of cancer., Li Q, Woods KW, Thomas S, Zhu GD, Packard G, Fisher J, Li T, Gong J, Dinges J, Song X, Abrams J, Luo Y, Johnson EF, Shi Y, Liu X, Klinghofer V, Des Jong R, Oltersdorf T, Stoll VS, Jakob CG, Rosenberg SH, Giranda VL, Bioorg Med Chem Lett. 2006 Apr 1;16(7):2000-7. Epub 2006 Jan 18. PMID:16413780
Page seeded by OCA on Mon Jul 28 12:45:57 2008
Categories: Bos taurus | Non-specific serine/threonine protein kinase | Single protein | Abrams, J. | Dinges, J. | Fisher, J. | Giranda, V L. | Gong, J. | Jakob, C G. | Johnson, E F. | Jong, R Des. | Klinghofer, V. | Li, Q. | Li, T. | Liu, X. | Luo, Y. | Oltersdorf, T. | Packard, G. | Rosenberg, S H. | Shi, Y. | Song, X. | Stoll, V S. | Thomas, S. | Woods, K W. | Zhu, G D. | Akt inhibitor | Protein kinase some
