2fzp

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Image:2fzp.png

Template:STRUCTURE 2fzp

Crystal structure of the USP8 interaction domain of human NRDP1

Template:ABSTRACT PUBMED 17035239

About this Structure

2FZP is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Amino-terminal dimerization, NRDP1-rhodanese interaction, and inhibited catalytic domain conformation of the ubiquitin-specific protease 8 (USP8)., Avvakumov GV, Walker JR, Xue S, Finerty PJ Jr, Mackenzie F, Newman EM, Dhe-Paganon S, J Biol Chem. 2006 Dec 8;281(49):38061-70. Epub 2006 Oct 11. PMID:17035239

Stabilization of the E3 ubiquitin ligase Nrdp1 by the deubiquitinating enzyme USP8., Wu X, Yen L, Irwin L, Sweeney C, Carraway KL 3rd, Mol Cell Biol. 2004 Sep;24(17):7748-57. PMID:15314180

Nrdp1-mediated degradation of the gigantic IAP, BRUCE, is a novel pathway for triggering apoptosis., Qiu XB, Markant SL, Yuan J, Goldberg AL, EMBO J. 2004 Feb 25;23(4):800-10. Epub 2004 Feb 12. PMID:14765125

An RBCC protein implicated in maintenance of steady-state neuregulin receptor levels., Diamonti AJ, Guy PM, Ivanof C, Wong K, Sweeney C, Carraway KL 3rd, Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):2866-71. Epub 2002 Feb 26. PMID:11867753

FLRF, a novel evolutionarily conserved RING finger gene, is differentially expressed in mouse fetal and adult hematopoietic stem cells and progenitors., Abdullah JM, Li X, Nachtman RG, Jurecic R, Blood Cells Mol Dis. 2001 Jan-Feb;27(1):320-33. PMID:11358394

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