2iko
From Proteopedia
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2iko, resolution 1.90Å () | |||||||||
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Ligands: | |||||||||
Gene: | REN (Homo sapiens) | ||||||||
Activity: | Renin, with EC number 3.4.23.15 | ||||||||
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Resources: | FirstGlance, OCA, RCSB, PDBsum | ||||||||
Coordinates: | save as pdb, mmCIF, xml |
Contents |
Crystal Structure of Human Renin Complexed with Inhibitor
Template:ABSTRACT PUBMED 17113558
Disease
Known disease associated with this structure: Renal tubular dysgenesis OMIM:[179820], Hyperproreninemia OMIM:[179820]
About this Structure
2IKO is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Binding thermodynamics of substituted diaminopyrimidine renin inhibitors., Sarver RW, Peevers J, Cody WL, Ciske FL, Dyer J, Emerson SD, Hagadorn JC, Holsworth DD, Jalaie M, Kaufman M, Mastronardi M, McConnell P, Powell NA, Quin J 3rd, Van Huis CA, Zhang E, Mochalkin I, Anal Biochem. 2007 Jan 1;360(1):30-40. Epub 2006 Oct 30. PMID:17113558
Page seeded by OCA on Mon Jul 28 21:42:48 2008