2o2f
From Proteopedia
Contents |
Solution structure of the anti-apoptotic protein Bcl-2 in complex with an acyl-sulfonamide-based ligand
Template:ABSTRACT PUBMED 17256834
Disease
Known disease associated with this structure: Leukemia/lymphoma, B-cell OMIM:[151430]
About this Structure
2O2F is a Single protein structure of sequence from Homo sapiens. Full experimental information is available from OCA.
Reference
Studies leading to potent, dual inhibitors of Bcl-2 and Bcl-xL., Bruncko M, Oost TK, Belli BA, Ding H, Joseph MK, Kunzer A, Martineau D, McClellan WJ, Mitten M, Ng SC, Nimmer PM, Oltersdorf T, Park CM, Petros AM, Shoemaker AR, Song X, Wang X, Wendt MD, Zhang H, Fesik SW, Rosenberg SH, Elmore SW, J Med Chem. 2007 Feb 22;50(4):641-62. Epub 2007 Jan 26. PMID:17256834
Page seeded by OCA on Mon Jul 28 20:29:35 2008
Categories: Homo sapiens | Single protein | Belli, B A. | Bruncko, M. | Ding, H. | Elmore, S W. | Fesik, S W. | Joseph, M K. | Kunzer, A. | Martineau, D. | McClellan, W J. | Mitten, M. | Ng, S C. | Nimmer, P M. | Oltersdorf, T. | Oost, T K. | Park, C M. | Petros, A M. | Rosenberg, S H. | Shoemaker, A R. | Song, X. | Wang, X. | Wendt, M D. | Zhang, H. | Apoptosis | Bcl | Complex | Nmr
