1h2s
From Proteopedia
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MOLECULAR BASIS OF TRANSMENBRANE SIGNALLING BY SENSORY RHODOPSIN II-TRANSDUCER COMPLEX
Overview
Microbial rhodopsins, which constitute a family of seven-helix membrane, proteins with retinal as a prosthetic group, are distributed throughout, the Bacteria, Archaea and Eukaryota. This family of photoactive proteins, uses a common structural design for two distinct functions: light-driven, ion transport and phototaxis. The sensors activate a signal transduction, chain similar to that of the two-component system of eubacterial, chemotaxis. The link between the photoreceptor and the following, cytoplasmic signal cascade is formed by a transducer molecule that binds, tightly and specifically to its cognate receptor by means of two, transmembrane helices (TM1 and TM2). It is thought that light excitation, of sensory rhodopsin II from Natronobacterium pharaonis (SRII) in complex, with its ... [(full description)]
About this Structure
1H2S is a [Protein complex] structure of sequences from [Natronomonas pharaonis] with BOG and RET as [ligands]. Structure known Active Site: BOG. Full crystallographic information is available from [OCA].
Reference
Molecular basis of transmembrane signalling by sensory rhodopsin II-transducer complex., Gordeliy VI, Labahn J, Moukhametzianov R, Efremov R, Granzin J, Schlesinger R, Buldt G, Savopol T, Scheidig AJ, Klare JP, Engelhard M, Nature. 2002 Oct 3;419(6906):484-7. PMID:12368857
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