2pwl

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Template:STRUCTURE 2pwl

Crystal Strucure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic N549H Mutation Responsible for Crouzon Syndrome.

Template:ABSTRACT PUBMED 17803937

About this Structure

2PWL is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases., Chen H, Ma J, Li W, Eliseenkova AV, Xu C, Neubert TA, Miller WT, Mohammadi M, Mol Cell. 2007 Sep 7;27(5):717-30. PMID:17803937

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