This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1a0t
From Proteopedia
|
SUCROSE-SPECIFIC PORIN, WITH BOUND SUCROSE MOLECULES
Overview
The X-ray structure of a sucrose-specific porin (ScrY) from Salmonella typhimurium has been determined by multiple isomorphous replacement at 2.4 A resolution both in its uncomplexed form and with bound sucrose. ScrY is a noncrystallographic trimer of identical subunits, each with 413 structurally well-defined amino acids. A monomer is built up of 18 anti-parallel beta-strands surrounding a hydrophilic pore, with a topology closely similar to that of maltoporin. Two non-overlapping sucrose-binding sites were identified in difference Fourier maps. The higher permeability for sucrose of ScrY as compared to maltoporin is mainly accounted for by differences in their pore-lining residues.
About this Structure
1A0T is a Single protein structure of sequence from Salmonella typhimurium with and as ligands. Full crystallographic information is available from OCA.
Reference
Structure of the sucrose-specific porin ScrY from Salmonella typhimurium and its complex with sucrose., Forst D, Welte W, Wacker T, Diederichs K, Nat Struct Biol. 1998 Jan;5(1):37-46. PMID:9437428
Page seeded by OCA on Thu Feb 21 11:39:36 2008
