1owt

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Template:STRUCTURE 1owt

Contents 1 Structure of the Alzheimer's disease amyloid precursor protein copper binding domain 2 Disease 3 About this Structure 4 Reference

Structure of the Alzheimer's disease amyloid precursor protein copper binding domain

Template:ABSTRACT PUBMED 12611883

Disease

Known disease associated with this structure: Alzheimer disease-1, APP-related OMIM:[104760], Amyloidosis, cerebroarterial, Dutch type OMIM:[104760], Amyloidosis, cerebroarterial, Iowa type OMIM:[104760]

About this Structure

1OWT is a Single protein structure of sequence from Homo sapiens. Additional information on 1OWT is available in a page on Amyloid-beta Precursor Protein at the RCSB PDB Molecule of the Month. Full experimental information is available from OCA.

Reference

Structure of the Alzheimer's disease amyloid precursor protein copper binding domain. A regulator of neuronal copper homeostasis., Barnham KJ, McKinstry WJ, Multhaup G, Galatis D, Morton CJ, Curtain CC, Williamson NA, White AR, Hinds MG, Norton RS, Beyreuther K, Masters CL, Parker MW, Cappai R, J Biol Chem. 2003 May 9;278(19):17401-7. Epub 2003 Feb 28. PMID:12611883

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