1a1a

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Image:1a1a.png

Template:STRUCTURE 1a1a

Contents

C-SRC (SH2 DOMAIN WITH C188A MUTATION) COMPLEXED WITH ACE-FORMYL PHOSPHOTYR-GLU-(N,N-DIPENTYL AMINE)

Template:ABSTRACT PUBMED 9174343

Disease

Known disease associated with this structure: Colon cancer, advanced OMIM:[190090]

About this Structure

1A1A is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Charifson PS, Shewchuk LM, Rocque W, Hummel CW, Jordan SR, Mohr C, Pacofsky GJ, Peel MR, Rodriguez M, Sternbach DD, Consler TG. Peptide ligands of pp60(c-src) SH2 domains: a thermodynamic and structural study. Biochemistry. 1997 May 27;36(21):6283-93. PMID:9174343 doi:http://dx.doi.org/10.1021/bi970019n

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