1b72

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Image:1b72.png

Template:STRUCTURE 1b72

Contents

PBX1, HOMEOBOX PROTEIN HOX-B1/DNA TERNARY COMPLEX

Template:ABSTRACT PUBMED 10052460

Disease

Known disease associated with this structure: Leukemia, acute pre-B-cell OMIM:[176310]

About this Structure

1B72 is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Piper DE, Batchelor AH, Chang CP, Cleary ML, Wolberger C. Structure of a HoxB1-Pbx1 heterodimer bound to DNA: role of the hexapeptide and a fourth homeodomain helix in complex formation. Cell. 1999 Feb 19;96(4):587-97. PMID:10052460

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