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1e26

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Image:1e26.png

Template:STRUCTURE 1e26

DESIGN, SYNTHESIS AND X-RAY CRYSTAL STRUCTURE OF A POTENT DUAL INHIBITOR OF THYMIDYLATE SYNTHASE AND DIHYDROFOLATE REDUCTASE AS AN ANTITUMOR AGENT.

Template:ABSTRACT PUBMED 11052789

About this Structure

1E26 is a 1 chain structure of sequence from Pneumocystis carinii. Full crystallographic information is available from OCA.

Reference

  • Gangjee A, Yu J, McGuire JJ, Cody V, Galitsky N, Kisliuk RL, Queener SF. Design, synthesis, and X-ray crystal structure of a potent dual inhibitor of thymidylate synthase and dihydrofolate reductase as an antitumor agent. J Med Chem. 2000 Oct 19;43(21):3837-51. PMID:11052789

Page seeded by OCA on Tue Feb 17 14:08:56 2009

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