1hv7

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Image:1hv7.png

Template:STRUCTURE 1hv7

PORCINE PANCREATIC ELASTASE COMPLEXED WITH GW311616A

Template:ABSTRACT PUBMED 11294386

About this Structure

1HV7 is a 1 chain structure of sequence from Sus scrofa. Full crystallographic information is available from OCA.

Reference

  • Macdonald SJ, Dowle MD, Harrison LA, Shah P, Johnson MR, Inglis GG, Clarke GD, Smith RA, Humphreys D, Molloy CR, Amour A, Dixon M, Murkitt G, Godward RE, Padfield T, Skarzynski T, Singh OM, Kumar KA, Fleetwood G, Hodgson ST, Hardy GW, Finch H. The discovery of a potent, intracellular, orally bioavailable, long duration inhibitor of human neutrophil elastase--GW311616A a development candidate. Bioorg Med Chem Lett. 2001 Apr 9;11(7):895-8. PMID:11294386

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