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1hvy

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Revision as of 08:07, 17 February 2009 by OCA (Talk | contribs)
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Image:1hvy.png


PDB ID 1hvy

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1hvy, resolution 1.90Å ()
Ligands: , ,
Non-Standard Residues:
Activity: Thymidylate synthase, with EC number 2.1.1.45
Resources: FirstGlance, OCA, RCSB, PDBsum
Coordinates: save as pdb, mmCIF, xml



Human thymidylate synthase complexed with dUMP and Raltitrexed, an antifolate drug, is in the closed conformation

Template:ABSTRACT PUBMED 11329255

About this Structure

1HVY is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Phan J, Koli S, Minor W, Dunlap RB, Berger SH, Lebioda L. Human thymidylate synthase is in the closed conformation when complexed with dUMP and raltitrexed, an antifolate drug. Biochemistry. 2001 Feb 20;40(7):1897-902. PMID:11329255

Page seeded by OCA on Tue Feb 17 10:07:31 2009

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