1jlb
From Proteopedia
CRYSTAL STRUCTURE OF Y181C MUTANT HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH NEVIRAPINE
Template:ABSTRACT PUBMED 11575933
About this Structure
1JLB is a Protein complex structure of sequences from Human immunodeficiency virus type 1 (isolate hxb2). Additional information on 1JLB is available in a page on Reverse Transcriptase at the RCSB PDB Molecule of the Month. Full crystallographic information is available from OCA.
Reference
Structural mechanisms of drug resistance for mutations at codons 181 and 188 in HIV-1 reverse transcriptase and the improved resilience of second generation non-nucleoside inhibitors., Ren J, Nichols C, Bird L, Chamberlain P, Weaver K, Short S, Stuart DI, Stammers DK, J Mol Biol. 2001 Sep 28;312(4):795-805. PMID:11575933
Page seeded by OCA on Wed Jul 23 11:08:45 2008
Categories: Protein complex | RNA-directed DNA polymerase | Reverse Transcriptase | Bird, L. | Chamberlain, P. | Nichols, C. | Ren, J. | Short, S. | Stammers, D K. | Stuart, D I. | Weaver, K. | Aid | Drug design | Drug resistance mutation | Hiv-1 reverse transcriptase | Nevirapine | Non-nucleoside inhibitor