1jm7

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Template:STRUCTURE 1jm7

Contents

Solution structure of the BRCA1/BARD1 RING-domain heterodimer

Template:ABSTRACT PUBMED 11573085

Disease

Known disease associated with this structure: Breast cancer-1 OMIM:[113705], Breast-ovarian cancer OMIM:[113705], Ovarian cancer OMIM:[113705], Papillary serous carcinoma of the peritoneum OMIM:[113705], Breast cancer, susceptibility to OMIM:[601593]

About this Structure

1JM7 is a 2 chains structure of sequences from Homo sapiens. Full experimental information is available from OCA.

Reference

  • Brzovic PS, Rajagopal P, Hoyt DW, King MC, Klevit RE. Structure of a BRCA1-BARD1 heterodimeric RING-RING complex. Nat Struct Biol. 2001 Oct;8(10):833-7. PMID:11573085 doi:10.1038/nsb1001-833

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