3d94

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Image:3d94.png

Template:STRUCTURE 3d94

Contents

Crystal structure of the insulin-like growth factor-1 receptor kinase in complex with PQIP

Template:ABSTRACT PUBMED 18566589

Disease

Known disease associated with this structure: Insulin-like growth factor I, resistance to OMIM:[147370]

About this Structure

3D94 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Wu J, Li W, Craddock BP, Foreman KW, Mulvihill MJ, Ji QS, Miller WT, Hubbard SR. Small-molecule inhibition and activation-loop trans-phosphorylation of the IGF1 receptor. EMBO J. 2008 Jul 23;27(14):1985-94. Epub 2008 Jun 19. PMID:18566589 doi:10.1038/emboj.2008.116

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