2vuk
From Proteopedia
STRUCTURE OF THE P53 CORE DOMAIN MUTANT Y220C BOUND TO THE STABILIZING SMALL-MOLECULE DRUG PHIKAN083
Template:ABSTRACT PUBMED 17015838
About this Structure
2VUK is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Structural basis for understanding oncogenic p53 mutations and designing rescue drugs., Joerger AC, Ang HC, Fersht AR, Proc Natl Acad Sci U S A. 2006 Oct 10;103(41):15056-61. Epub 2006 Oct 2. PMID:17015838
Page seeded by OCA on Wed Aug 6 09:59:49 2008
Categories: Homo sapiens | Single protein | Boeckler, F M. | Fersht, A R. | Joerger, A C. | Acetylation | Activator | Alternative splicing | Anti-oncogene | Apoptosis | Cancer | Cell cycle | Covalent protein-rna linkage | Cytoplasm | Disease mutation | Dna binding | Dna-binding | Dna-binding protein | Endoplasmic reticulum | Glycoprotein | Host-virus interaction | Li-fraumeni syndrome | Metal binding | Metal-binding | Methylation | Nuclear protein | Nucleus | P53 dna- binding domain | Phosphoprotein | Polymorphism | Protein stabilization | Second-site suppressor mutation | Small-molecule drug | Superstable mutant | Surface crevice | Transcription | Transcription regulation | Tumor suppressor | Ubl conjugation | Virtual screening | Zinc
