2qcg

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Template:STRUCTURE 2qcg

Contents 1 Crystal structure of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase bound to 5-bromo-UMP 2 Disease 3 About this Structure 4 Reference

Crystal structure of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase bound to 5-bromo-UMP

Template:ABSTRACT PUBMED 18184586

Disease

Known disease associated with this structure: Oroticaciduria OMIM:[258900]

About this Structure

2QCG is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

• Wittmann JG, Heinrich D, Gasow K, Frey A, Diederichsen U, Rudolph MG. Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design. Structure. 2008 Jan;16(1):82-92. PMID:18184586 doi:http://dx.doi.org/10.1016/j.str.2007.10.020

Page seeded by OCA on Mon Feb 16 14:13:28 2009