2cn0

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Image:2cn0.png

Template:STRUCTURE 2cn0

COMPLEX OF RECOMBINANT HUMAN THROMBIN WITH A DESIGNED INHIBITOR

Template:ABSTRACT PUBMED 17001711

About this Structure

2CN0 is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Hoffmann-Roder A, Schweizer E, Egger J, Seiler P, Obst-Sander U, Wagner B, Kansy M, Banner DW, Diederich F. Mapping the fluorophilicity of a hydrophobic pocket: synthesis and biological evaluation of tricyclic thrombin inhibitors directing fluorinated alkyl groups into the p pocket. ChemMedChem. 2006 Nov;1(11):1205-15. PMID:17001711 doi:10.1002/cmdc.200600124

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