2opp

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Image:2opp.png

Template:STRUCTURE 2opp

Crystal Structure of HIV-1 Reverse Transcriptase in Complex with GW420867X.

Template:ABSTRACT PUBMED 17441703

About this Structure

2OPP is a 2 chains structure of sequences from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

  • Ren J, Nichols CE, Chamberlain PP, Weaver KL, Short SA, Chan JH, Kleim JP, Stammers DK. Relationship of potency and resilience to drug resistant mutations for GW420867X revealed by crystal structures of inhibitor complexes for wild-type, Leu100Ile, Lys101Glu, and Tyr188Cys mutant HIV-1 reverse transcriptases. J Med Chem. 2007 May 17;50(10):2301-9. Epub 2007 Apr 19. PMID:17441703 doi:http://dx.doi.org/10.1021/jm061117m

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