2gd4

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Image:2gd4.png

Template:STRUCTURE 2gd4

Contents

Crystal Structure of the Antithrombin-S195A Factor Xa-Pentasaccharide Complex

Template:ABSTRACT PUBMED 16619025

Disease

Known disease associated with this structure: Factor X deficiency OMIM:[227600]

About this Structure

2GD4 is a 6 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Johnson DJ, Li W, Adams TE, Huntington JA. Antithrombin-S195A factor Xa-heparin structure reveals the allosteric mechanism of antithrombin activation. EMBO J. 2006 May 3;25(9):2029-37. Epub 2006 Apr 13. PMID:16619025

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