2ojf

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Template:STRUCTURE 2ojf

Crystal structure of Protein Kinase A in complex with Pyridine-Pyrazolopyridine based inhibitors

Template:ABSTRACT PUBMED 17258463

About this Structure

2OJF is a 2 chains structure of sequences from Bos taurus. Full crystallographic information is available from OCA.

Reference

  • Zhu GD, Gong J, Gandhi VB, Woods K, Luo Y, Liu X, Guan R, Klinghofer V, Johnson EF, Stoll VS, Mamo M, Li Q, Rosenberg SH, Giranda VL. Design and synthesis of pyridine-pyrazolopyridine-based inhibitors of protein kinase B/Akt. Bioorg Med Chem. 2007 Mar 15;15(6):2441-52. Epub 2007 Jan 17. PMID:17258463 doi:10.1016/j.bmc.2007.01.010

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