2hwh

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Image:2hwh.png

Template:STRUCTURE 2hwh

HCV NS5B allosteric inhibitor complex

Template:ABSTRACT PUBMED 16934455

About this Structure

2HWH is a 2 chains structure of sequences from Hepatitis c virus. Full crystallographic information is available from OCA.

Reference

  • Yan S, Appleby T, Larson G, Wu JZ, Hamatake R, Hong Z, Yao N. Structure-based design of a novel thiazolone scaffold as HCV NS5B polymerase allosteric inhibitors. Bioorg Med Chem Lett. 2006 Nov 15;16(22):5888-91. Epub 2006 Aug 24. PMID:16934455 doi:10.1016/j.bmcl.2006.08.056

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