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2g94
From Proteopedia
Crystal structure of beta-secretase bound to a potent and highly selective inhibitor.
Template:ABSTRACT PUBMED 16620080
About this Structure
2G94 is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Ghosh AK, Kumaragurubaran N, Hong L, Lei H, Hussain KA, Liu CF, Devasamudram T, Weerasena V, Turner R, Koelsch G, Bilcer G, Tang J. Design, synthesis and X-ray structure of protein-ligand complexes: important insight into selectivity of memapsin 2 (beta-secretase) inhibitors. J Am Chem Soc. 2006 Apr 26;128(16):5310-1. PMID:16620080 doi:10.1021/ja058636j
Page seeded by OCA on Mon Feb 16 20:58:52 2009
Categories: Homo sapiens | Memapsin 2 | Ghosh, A. | Hong, L. | Tang, J. | Alzheimer's disease | Asp2 | Aspartic protease | Bace | Beta secretase | Drug design | Memapsin | Protease inhibitor
