2fak

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Image:2fak.png

Template:STRUCTURE 2fak

Crystal structure of Salinosporamide A in complex with the yeast 20S proteasome

Template:ABSTRACT PUBMED 16608349

About this Structure

2FAK is a 28 chains structure of sequences from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Reference

  • Groll M, Huber R, Potts BC. Crystal structures of Salinosporamide A (NPI-0052) and B (NPI-0047) in complex with the 20S proteasome reveal important consequences of beta-lactone ring opening and a mechanism for irreversible binding. J Am Chem Soc. 2006 Apr 19;128(15):5136-41. PMID:16608349 doi:10.1021/ja058320b

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