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1s8o

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Revision as of 22:11, 16 February 2009 by OCA (Talk | contribs)
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Image:1s8o.png


PDB ID 1s8o

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1s8o, resolution 2.60Å ()
Ligands:
Gene: EPHX2 (Homo sapiens)
Activity: Hydrolase, with EC number and 3.3.2.10 3.3.2.9 and 3.3.2.10
Related: 1vj5
Resources: FirstGlance, OCA, RCSB, PDBsum
Coordinates: save as pdb, mmCIF, xml



Contents

Human soluble Epoxide Hydrolase

Template:ABSTRACT PUBMED 15096040

Disease

Known disease associated with this structure: Hypercholesterolemia, familial, due to LDLR defect, modifier of OMIM:[132811]

About this Structure

1S8O is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Gomez GA, Morisseau C, Hammock BD, Christianson DW. Structure of human epoxide hydrolase reveals mechanistic inferences on bifunctional catalysis in epoxide and phosphate ester hydrolysis. Biochemistry. 2004 Apr 27;43(16):4716-23. PMID:15096040 doi:10.1021/bi036189j

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