2o2k

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Image:2o2k.png

Template:STRUCTURE 2o2k

Contents

Crystal Structure of the Activation Domain of Human Methionine Synthase Isoform/Mutant D963E/K1071N

Template:ABSTRACT PUBMED 17288554

Disease

Known disease associated with this structure: Methylcobalamin deficiency, cblG type OMIM:[156570], Cleft lip/palate, susceptibility to OMIM:[156570], Down syndrome, susceptibility to OMIM:[156570], Neural tube defects, folate-sensitive, susceptibility to OMIM:[156570]

About this Structure

2O2K is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Wolthers KR, Toogood HS, Jowitt TA, Marshall KR, Leys D, Scrutton NS. Crystal structure and solution characterization of the activation domain of human methionine synthase. FEBS J. 2007 Feb;274(3):738-50. PMID:17288554 doi:10.1111/j.1742-4658.2006.05618.x

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