1ony

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Template:STRUCTURE 1ony

Oxalyl-Aryl-Amino Benzoic Acid inhibitors of PTP1B, compound 17

Template:ABSTRACT PUBMED 12747781

About this Structure

1ONY is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Liu G, Szczepankiewicz BG, Pei Z, Janowick DA, Xin Z, Hajduk PJ, Abad-Zapatero C, Liang H, Hutchins CW, Fesik SW, Ballaron SJ, Stashko MA, Lubben T, Mika AK, Zinker BA, Trevillyan JM, Jirousek MR. Discovery and structure-activity relationship of oxalylarylaminobenzoic acids as inhibitors of protein tyrosine phosphatase 1B. J Med Chem. 2003 May 22;46(11):2093-103. PMID:12747781 doi:http://dx.doi.org/10.1021/jm0205696

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