1pwm

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Image:1pwm.png

Template:STRUCTURE 1pwm

Crystal structure of human Aldose Reductase complexed with NADP and Fidarestat

Template:ABSTRACT PUBMED 15146479

About this Structure

1PWM is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • El-Kabbani O, Darmanin C, Schneider TR, Hazemann I, Ruiz F, Oka M, Joachimiak A, Schulze-Briese C, Tomizaki T, Mitschler A, Podjarny A. Ultrahigh resolution drug design. II. Atomic resolution structures of human aldose reductase holoenzyme complexed with Fidarestat and Minalrestat: implications for the binding of cyclic imide inhibitors. Proteins. 2004 Jun 1;55(4):805-13. PMID:15146479 doi:10.1002/prot.20001

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