2pg2

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Image:2pg2.png

Template:STRUCTURE 2pg2

Crystal structure of KSP in complex with ADP and thiophene containing inhibitor 15

Template:ABSTRACT PUBMED 17498954

About this Structure

2PG2 is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Pinkerton AB, Lee TT, Hoffman TZ, Wang Y, Kahraman M, Cook TG, Severance D, Gahman TC, Noble SA, Shiau AK, Davis RL. Synthesis and SAR of thiophene containing kinesin spindle protein (KSP) inhibitors. Bioorg Med Chem Lett. 2007 Jul 1;17(13):3562-9. Epub 2007 Apr 29. PMID:17498954 doi:10.1016/j.bmcl.2007.04.076

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