2jyu

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Image:2jyu.png

Template:STRUCTURE 2jyu

Contents

Human Granulin C, isomer 2

Template:ABSTRACT PUBMED 18359860

Disease

Known disease associated with this structure: Frontotemporal lobar degeneration with ubiquitin-positive inclusions OMIM:[138945]

About this Structure

2JYU is a 1 chain structure of sequence from Homo sapiens. Full experimental information is available from OCA.

Reference

  • Tolkatchev D, Malik S, Vinogradova A, Wang P, Chen Z, Xu P, Bennett HP, Bateman A, Ni F. Structure dissection of human progranulin identifies well-folded granulin/epithelin modules with unique functional activities. Protein Sci. 2008 Apr;17(4):711-24. PMID:18359860 doi:http://dx.doi.org/17/4/711

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