2o8h

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Template:STRUCTURE 2o8h

Crystal structure of the catalytic domain of rat phosphodiesterase 10A

Template:ABSTRACT PUBMED 17228859

About this Structure

2O8H is a 1 chain structure of sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  • Chappie TA, Humphrey JM, Allen MP, Estep KG, Fox CB, Lebel LA, Liras S, Marr ES, Menniti FS, Pandit J, Schmidt CJ, Tu M, Williams RD, Yang FV. Discovery of a series of 6,7-dimethoxy-4-pyrrolidylquinazoline PDE10A inhibitors. J Med Chem. 2007 Jan 25;50(2):182-5. PMID:17228859 doi:10.1021/jm060653b

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