2fzb

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Image:2fzb.png

Template:STRUCTURE 2fzb

Human Aldose Reductase complexed with four tolrestat molecules at 1.5 A resolution.

Template:ABSTRACT PUBMED 16952371

About this Structure

2FZB is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Steuber H, Zentgraf M, Gerlach C, Sotriffer CA, Heine A, Klebe G. Expect the unexpected or caveat for drug designers: multiple structure determinations using aldose reductase crystals treated under varying soaking and co-crystallisation conditions. J Mol Biol. 2006 Oct 13;363(1):174-87. Epub 2006 Aug 9. PMID:16952371 doi:http://dx.doi.org/10.1016/j.jmb.2006.08.011

Page seeded by OCA on Tue Feb 17 09:12:20 2009

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