1py4

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Image:1py4.png

Template:STRUCTURE 1py4

Contents

Beta2 microglobulin mutant H31Y displays hints for amyloid formations

Template:ABSTRACT PUBMED 14698299

Disease

Known disease associated with this structure: Hypoproteinemia, hypercatabolic OMIM:[109700]

About this Structure

1PY4 is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Rosano C, Zuccotti S, Mangione P, Giorgetti S, Bellotti V, Pettirossi F, Corazza A, Viglino P, Esposito G, Bolognesi M. beta2-microglobulin H31Y variant 3D structure highlights the protein natural propensity towards intermolecular aggregation. J Mol Biol. 2004 Jan 23;335(4):1051-64. PMID:14698299

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