2b5j

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Template:STRUCTURE 2b5j

Crystal structure of HIV-1 reverse transcriptase (RT) in complex with JANSSEN-R165481

Template:ABSTRACT PUBMED 16302798

About this Structure

2B5J is a 2 chains structure of sequences from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

  • Himmel DM, Das K, Clark AD Jr, Hughes SH, Benjahad A, Oumouch S, Guillemont J, Coupa S, Poncelet A, Csoka I, Meyer C, Andries K, Nguyen CH, Grierson DS, Arnold E. Crystal structures for HIV-1 reverse transcriptase in complexes with three pyridinone derivatives: a new class of non-nucleoside inhibitors effective against a broad range of drug-resistant strains. J Med Chem. 2005 Dec 1;48(24):7582-91. PMID:16302798 doi:10.1021/jm0500323

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