2hiz

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Template:STRUCTURE 2hiz

Crystal Structure of human beta-secretase (BACE) in the presence of an inhibitor

Template:ABSTRACT PUBMED 17046251

About this Structure

2HIZ is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Freskos JN, Fobian YM, Benson TE, Bienkowski MJ, Brown DL, Emmons TL, Heintz R, Laborde A, McDonald JJ, Mischke BV, Molyneaux JM, Moon JB, Mullins PB, Bryan Prince D, Paddock DJ, Tomasselli AG, Winterrowd G. Design of potent inhibitors of human beta-secretase. Part 1. Bioorg Med Chem Lett. 2007 Jan 1;17(1):73-7. Epub 2006 Oct 4. PMID:17046251 doi:10.1016/j.bmcl.2006.09.092

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