1xbb

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Image:1xbb.png

Template:STRUCTURE 1xbb

Crystal structure of the syk tyrosine kinase domain with Gleevec

Template:ABSTRACT PUBMED 15507431

About this Structure

1XBB is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Atwell S, Adams JM, Badger J, Buchanan MD, Feil IK, Froning KJ, Gao X, Hendle J, Keegan K, Leon BC, Muller-Dieckmann HJ, Nienaber VL, Noland BW, Post K, Rajashankar KR, Ramos A, Russell M, Burley SK, Buchanan SG. A novel mode of Gleevec binding is revealed by the structure of spleen tyrosine kinase. J Biol Chem. 2004 Dec 31;279(53):55827-32. Epub 2004 Oct 26. PMID:15507431 doi:10.1074/jbc.M409792200

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