1uk1

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Image:1uk1.png

Template:STRUCTURE 1uk1

Crystal structure of human poly(ADP-ribose) polymerase complexed with a potent inhibitor

Template:ABSTRACT PUBMED 15293985

About this Structure

1UK1 is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Hattori K, Kido Y, Yamamoto H, Ishida J, Kamijo K, Murano K, Ohkubo M, Kinoshita T, Iwashita A, Mihara K, Yamazaki S, Matsuoka N, Teramura Y, Miyake H. Rational approaches to discovery of orally active and brain-penetrable quinazolinone inhibitors of poly(ADP-ribose)polymerase. J Med Chem. 2004 Aug 12;47(17):4151-4. PMID:15293985 doi:10.1021/jm0499256

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