2v10

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Image:2v10.png

Template:STRUCTURE 2v10

CRYSTAL STRUCTURE OF RENIN WITH INHIBITOR 9

Template:ABSTRACT PUBMED 10903938

About this Structure

2V10 is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Rahuel J, Rasetti V, Maibaum J, Rueger H, Goschke R, Cohen NC, Stutz S, Cumin F, Fuhrer W, Wood JM, Grutter MG. Structure-based drug design: the discovery of novel nonpeptide orally active inhibitors of human renin. Chem Biol. 2000 Jul;7(7):493-504. PMID:10903938
  • Rahuel J, Priestle JP, Grutter MG. The crystal structures of recombinant glycosylated human renin alone and in complex with a transition state analog inhibitor. J Struct Biol. 1991 Dec;107(3):227-36. PMID:1807356

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