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3bjc
From Proteopedia
Crystal structure of the PDE5A catalytic domain in complex with a novel inhibitor
Template:ABSTRACT PUBMED 18346713
About this Structure
3BJC is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Chen G, Wang H, Robinson H, Cai J, Wan Y, Ke H. An insight into the pharmacophores of phosphodiesterase-5 inhibitors from synthetic and crystal structural studies. Biochem Pharmacol. 2008 May 1;75(9):1717-28. Epub 2008 Feb 12. PMID:18346713 doi:10.1016/j.bcp.2008.01.019
Page seeded by OCA on Tue Feb 17 18:41:44 2009
Categories: 3',5'-cyclic-GMP phosphodiesterase | Homo sapiens | Cai, J. | Chen, G. | Howard, R. | Ke, H. | Wan, Y. | Wang, H. | Allosteric enzyme | Alternative splicing | Cgmp | Cgmp-binding | Crystal structure | Erectile dysfunction | Hydrolase | Inhibitor design | Magnesium | Metal-binding | Nucleotide-binding | Pde5 | Phosphoprotein | Polymorphism | Zinc
