1pkx

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Image:1pkx.png

Template:STRUCTURE 1pkx

Contents

Crystal Structure of human ATIC in complex with XMP

Template:ABSTRACT PUBMED 14756553

Disease

Known disease associated with this structure: AICA-ribosiduria due to ATIC deficiency OMIM:[601731]

About this Structure

1PKX is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Wolan DW, Cheong CG, Greasley SE, Wilson IA. Structural insights into the human and avian IMP cyclohydrolase mechanism via crystal structures with the bound XMP inhibitor. Biochemistry. 2004 Feb 10;43(5):1171-83. PMID:14756553 doi:10.1021/bi030162i

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