3bg9

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Template:STRUCTURE 3bg9

Contents 1 Crystal Structure of Human Pyruvate Carboxylase (missing the biotin carboxylase domain at the N-terminus) F1077A Mutant 2 Disease 3 About this Structure 4 Reference

Crystal Structure of Human Pyruvate Carboxylase (missing the biotin carboxylase domain at the N-terminus) F1077A Mutant

Template:ABSTRACT PUBMED 18297087

Disease

Known disease associated with this structure: Pyruvate carboxylase deficiency OMIM:[608786], Thrombophilia due to protein C deficiency, autosomal dominant OMIM:[612283], Thrombophilia due to protein C deficiency, autosomal recessive OMIM:[612283]

About this Structure

3BG9 is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

• Xiang S, Tong L. Crystal structures of human and Staphylococcus aureus pyruvate carboxylase and molecular insights into the carboxyltransfer reaction. Nat Struct Mol Biol. 2008 Mar;15(3):295-302. Epub 2008 Feb 24. PMID:18297087 doi:10.1038/nsmb.1393

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