2jg4

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Image:2jg4.png

Template:STRUCTURE 2jg4

SUBSTRATE-FREE IDE STRUCTURE IN ITS CLOSED CONFORMATION

Template:ABSTRACT PUBMED 17613531

About this Structure

2JG4 is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Im H, Manolopoulou M, Malito E, Shen Y, Zhao J, Neant-Fery M, Sun CY, Meredith SC, Sisodia SS, Leissring MA, Tang WJ. Structure of substrate-free human insulin-degrading enzyme (IDE) and biophysical analysis of ATP-induced conformational switch of IDE. J Biol Chem. 2007 Aug 31;282(35):25453-63. Epub 2007 Jul 5. PMID:17613531 doi:10.1074/jbc.M701590200

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