1tfq

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Image:1tfq.png

Template:STRUCTURE 1tfq

NMR Structure of an Antagonists of the XIAP-Caspase-9 Interaction Complexed to the BIR3 domain of XIAP

Template:ABSTRACT PUBMED 15317454

About this Structure

1TFQ is a 1 chain structure of sequence from Homo sapiens. Full experimental information is available from OCA.

Reference

  • Oost TK, Sun C, Armstrong RC, Al-Assaad AS, Betz SF, Deckwerth TL, Ding H, Elmore SW, Meadows RP, Olejniczak ET, Oleksijew A, Oltersdorf T, Rosenberg SH, Shoemaker AR, Tomaselli KJ, Zou H, Fesik SW. Discovery of potent antagonists of the antiapoptotic protein XIAP for the treatment of cancer. J Med Chem. 2004 Aug 26;47(18):4417-26. PMID:15317454 doi:http://dx.doi.org/10.1021/jm040037k

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