2qd5

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Template:STRUCTURE 2qd5

Contents

Structure of wild type human ferrochelatase in complex with a lead-porphyrin compound

Template:ABSTRACT PUBMED 17884090

Disease

Known disease associated with this structure: Protoporphyria, erythropoietic, autosomal dominant OMIM:[612386], Protoporphyria, erythropoietic, autosomal recessive OMIM:[612386]

About this Structure

2QD5 is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Medlock AE, Dailey TA, Ross TA, Dailey HA, Lanzilotta WN. A pi-helix switch selective for porphyrin deprotonation and product release in human ferrochelatase. J Mol Biol. 2007 Nov 2;373(4):1006-16. Epub 2007 Aug 23. PMID:17884090 doi:10.1016/j.jmb.2007.08.040

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