2oqi

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Image:2oqi.png

Template:STRUCTURE 2oqi

Human Dipeptidyl Peptidase IV (DPP4) with Piperidinone-constrained phenethylamine

Template:ABSTRACT PUBMED 17367123

About this Structure

2OQI is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Pei Z, Li X, von Geldern TW, Longenecker K, Pireh D, Stewart KD, Backes BJ, Lai C, Lubben TH, Ballaron SJ, Beno DW, Kempf-Grote AJ, Sham HL, Trevillyan JM. Discovery and structure-activity relationships of piperidinone- and piperidine-constrained phenethylamines as novel, potent, and selective dipeptidyl peptidase IV inhibitors. J Med Chem. 2007 Apr 19;50(8):1983-7. Epub 2007 Mar 17. PMID:17367123 doi:10.1021/jm061436d

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