2f8z

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Template:STRUCTURE 2f8z

Crystal structure of human FPPS in complex with zoledronate and isopentenyl diphosphate

Template:ABSTRACT PUBMED 16892359

About this Structure

2F8Z is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Rondeau JM, Bitsch F, Bourgier E, Geiser M, Hemmig R, Kroemer M, Lehmann S, Ramage P, Rieffel S, Strauss A, Green JR, Jahnke W. Structural basis for the exceptional in vivo efficacy of bisphosphonate drugs. ChemMedChem. 2006 Feb;1(2):267-73. PMID:16892359 doi:10.1002/cmdc.200500059

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